Conference Programme
AGENDA
Monday, October 24
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Time |
Presentation/Topic |
Speaker
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17.00 -20.00 |
Registration
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19.00 – 20.00 |
Welcome Reception |
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Day 1 – Tuesday, October 25
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Time |
Presentation/Topic |
Speaker
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08.00-09.00 |
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Registration
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Welcoming Session – Chairpersons – Paata Imnadze (Georgia), Elisabeth Carniel (France) |
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09.00-09.10 |
Opening Speech: Ministry of Labor, Health and Social Affairs of Georgia |
Minister or Deputy Minister |
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09.10-09.20 |
Georgia National Academy of Sciences |
Giorgi Kvesitadze (President) |
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09.20-09.30 |
Welcoming addresses from donors and supporters |
Elizabeth George (DTRA, USA) |
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09.30-09.40 |
National center for Disease Control and Public Health (NCDC) |
Amiran Gamkrelidze, Director General |
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09.40-09.55 |
Georgian Biosafety Association |
Lela Bakanidze |
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09.55-10.15 |
Coffee Break |
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10.15-11.15 |
Opening Lecture “If Yersinia pestis made Yops in vitro, then…” |
Robert Brubaker (USA) |
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Session 1 – Bacteriology of Yersinia Chairpersons - Robert Brubaker (USA), Mikael Skurnik (Finland) |
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11.15-11.55 |
“Several Hfq-dependent alterations in physiology of Yersinia enterocolitica O:3 are mediated by derepression of the transcriptional regulator RovM” |
Mikael Skurnik (Finland) |
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11.55-12.10 |
“Structural Basis for Myf and Psa Fimbriae-Mediated Tropism of Pathogenic Strains of Yersinia for Host Tissues” |
Anton V. Zavialov (Finland) |
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12.10-12.25 |
"Genetics, Classification and Ecology of Yersinia pestis Strains from the Plague Foci of the Russian Federation and Neighboring Countries” |
Galina Eroshenko (Russia) |
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12.25-12.40 |
Structure, Function and Phylogenesis of Yersinia Fimbrial Adhesins Assembled via Classical and Non-Classical Chaperone/Usher Pathways |
Vladimir P. Zav’yalov (Finland) |
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12.40-12.55 |
Genetic Bases for the Difference in Pyrazinamidase Activity Between Pathogenic and Non-Pathogenic Yersinia |
Anne-Sophie Le Guern (France) |
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12.55-13.10 |
“Inverse Autotransport: the Mechanism of Type Ve Secretion” |
Jack C. Leo (Norway) |
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13.10-1400 |
Poster Session (topics, 1, 2, 3, 4), Lunch |
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Session 2 – Infection and Immunity of Yersinia Chairpersons – B. Joseph Hinnebusch (USA), Yinon Levy (Israel) |
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14.00-14.40 |
“The Life Stage of Yersinia pestis in the Flea Gut and How It Leads to Transmission” |
B. Joseph Hinnebusch (USA) |
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14.40-15.00 |
“Macrophage Resistance to Yersinia pestis - Induced Apoptosis“ |
Christian Demeure (France) |
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15.00-15.30 |
Poster Session (topics, 1, 2, 3, 4), Coffee Break |
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15.50-16.10 |
“The Yersinia pestis Capsule Antigen Induces Rapid Humoral Anti-Plague Immunity in a CD4+ T Helper Cell Independent Manner |
Yinon Levy (Israel)
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16.10-16.30 |
“Adjunctive Corticosteroid Treatment Against Yersinia pestis Improves Bacterial Clearance, Immunopathology and Survival in the Mouse Model of Bubonic Plague” |
Emanuelle Mamroud (Israel)
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16.30-16.50 |
“Improvement of Yersinia pestis Growth on BIN Selective Agar” |
Moshe Aftalion (Israel) |
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16.50-17.10 |
“Development of a Live Vaccine against Bubonic and Pneumonic Plague” |
Anne Derbise (France) |
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17.10-17.30 |
Q&A; Wrap - up |
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Day 2 – Wednesday, October 26
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Time |
Presentation/Topic |
Speaker
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Session 3 – Genomics and Evolution of Yersinia Chairpersons - Elisabeth Carniel (France), Revaz Solomonia (Georgia) |
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09.00-09.20 |
“A Single Introduction of Yersinia pestis to Brazil during the 3rd Plague Pandemic” |
David Wagner (USA) |
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09.20-09.40 |
“Within-Host Evolution of Y. enterocolitica during a Chronic |
Cyril Savin (France) |
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09.40-10.00 |
“Evolutionary Loss of O-antigen by Yersinia pestis Promotes Its Interaction with Murine SIGNR1 (CD209), Dissemination and Infection” |
Yang Kun (China) |
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10.00-10.20 |
Comparative Proteomic Studies of Yersinia pestis Strains Isolated from Natural Foci in the Republic of Georgia |
Revaz Solomonia (Georgia) |
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10.20-10.50 |
Poster Session (topics, 1, 2, 3, 4), Coffee Break |
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10.50-11.30 |
“Plasminogen Activation Directly Stimulates Pulmonary Inflammation via Caspase-1 and is Required to Cause Pneumonic Plague” |
Wyndham W. Lathem (USA) |
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Early Inactivation of a Single Adhesin Facilitated the Emergence of Primary Pneumonic Plague and the Potential Respiratory Transmission of Yersinia pestis |
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11.30-11.50 |
“ Genetic characterization of Yersinia pestis strains endemic in Georgia and neighboring Caucasus countries” |
Ekaterine Zhgenti (Georgia) |
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11.50-12.10 |
“Mechanism Study on a Plague Outbreak Driven by the Construction of a Large Reservoir in Southwest China (Surveillance from 2000-2015)” |
Xin Wang (China) |
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12.10-12.30 |
Q&A; Wrap - up |
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13.00-14.00 |
Poster Session (topics, 5, 6, 7, 8), Lunch |
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Session 4 – Pathogenesis of Yersiniosis Chairpersons – James Bartholomew (USA), Jeremy Ritzer (USA) |
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14.00-14.40 |
“Differences between a plague bubo and a Y. pseudotuberculosis lymphadenopathy” |
Elisabeth Carniel (France) |
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14.40-15.00 |
The Essential Gene Set and Ciprofloxacin-Resistance Gene Set of Yersinia pseudotuberculosis |
Brendan Wren (UK) |
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15.00-15.30 |
Poster Session (topics, 5, 6, 7, 8), Coffee Break |
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15.30-15.50 |
Spatial and Temporal Expression Dynamics of a Global Bacterial Transcriptional Regulator During Pneumonic Plague |
Jeremy T. Ritzert (USA) |
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15.50-16.10 |
Yersinia pseudotuberculosis Exploits CD209 Receptors to Promote Host Dissemination and Infection |
Tie Chen (China) |
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1610-1630 |
“Ail Protein of Yersinia pestis Involves the Early Host Dissemination in Pneumonic Plague” |
Ying-xia He (China) |
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1630-1650 |
“Y. pestis-Specific Destruction of Lymphatics in the Plague Bubo |
Hope O’Donnell (France) |
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1650-1710 |
“Plague Infection in Endemic Small Mammals in Madagascar” |
Soanandrasana Rahelinirina (Madagascar) |
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17.10-10.30 |
Q&A; Wrap - up |
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1830 |
Buses leave from the Holiday Inn to the Restaurant “the Shadow of Metekhi” |
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1900 |
Gram - Negative Banquet in the Restaurant “the Shadow of Metekhi” |
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Day 3 – Thursday, October 27
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Time |
Presentation/Topic |
Speaker
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Session 5 – Diagnosis, Surveillance, and Control of Enteric Yersinioses and Plague Chairpersons - Minoarisoa Rajerison (Madagascar), Revaz Solomonia (Georgia) |
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09.00-09.20 |
“Surveillance on Plague in Georgia” |
Lela Bakanidze (Georgia) |
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09.20-10.00 |
“Surveillance and Control of Rat-Associated Human Plague in Uganda” |
Kenneth L. Gage (USA) |
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10.00-10.20 |
“Pneumonic Plague Transmission, Moramanga Madagascar, in 2015” |
Minoarisoa Rajerison (Madagascar) |
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10.20-10.50 |
Poster Session (topics, 5, 6, 7, 8), Coffee Break |
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10.50-11.10 |
“Are Hypotheses Explaining Plague Activity Mutually Exclusive?” |
Michael Kosoy (USA) |
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11.10-11.30 |
“An Overview of Yersiniosis Epidemiology in New Zealand” |
Anne – Marie Perchec - Merien (New Zealand) |
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11.30-11.50 |
“Confirmation of Pathogenic Yersinia Using Real-Time PCR” |
Hugo Strydom (New Zealand) |
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11.50-12.10 |
“Pneumonic Plague Outbreak of Mandritsara: the Involvement of Traditional Healers” |
Voahangy Andrianaivoarimanana (Madagascar) |
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1210-1230 |
Q&A; Wrap - up |
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1300-1400 |
Poster Session (topics, 5, 6, 7, 8), Lunch |
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Session 6 – Epidemiology and Ecology of Yersinia Chairpersons - Nils Chr. Stenseth (Norway), Xin Wang (China) |
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14.00-15.00 |
"A Unified Biology: Six Blind Scientists and the Elephant in the Room, a Parable for Environmentally Mediated Diseases (with a Focus on Yersinia spp.” |
Nils Chr. Stenseth (Norway) |
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15.00 |
Coffee Break |
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15.30-15.50 |
“Plague in Brazil: Update” |
Alzira Almeida (Brazil) |
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15.50-16.10 |
“Plague in Iran: Its History and Current Status” |
Ehsan Mostafavi (Iran) |
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16.10-16.30 |
“The possible impact of climate warming for epizootic activity of Central Caucasian natural focus of plague” |
Vladimir Dubyanski (Russia) |
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16.10-17.10 |
Closing Lecture – “My 35 Years with Yersinia” |
Hans Wolf-Watz, (Sweden) |
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17.10-17.30 |
Closing the Symposium |
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Day 4 – Friday, October 28
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Time |
Event |
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09.30 |
Buses leave from the Holiday Inn to Lugar Center and Eliava Institute |
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10.00-12.00 |
Tour to the Richard Lugar Center for Public Health Research |
Tour to Eliava Institute of Bacteriophage, Microbiology and Virology |
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12.00 |
Buses leave from the Lugar Center and Eliava Institute to the Holiday Inn |
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13.00-14.00 |
Lunch |
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14.00 |
Time free for Sightseeing – Bus tour to ancient capital of Georgia - Mtskheta |
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